Vitamin B complex is used as a dietary supplement in patients with unhealthy dietary habits and those with increased requirements.

B complex vitamins include:

• Vitamin B12 (Cyanocobalamine)
• Thiamine
• Vitamin B2 (Riboflavin)
• Niacin
• Pyridoxine,
• Vitamin B9 (Folic acid)
• Biotin

Vitamin B complex Dose in Adults

Vitamin B complex as a Dietary supplement:

• General dosing guidelines:
  • One tablet or one capsule once a day.
  • For detail dosing, refer to specific product labeling

Vitamin B complex Dose in Childrens

Dosage of each B complex vitamin in children is mentioned in details in the respective sections of each vitamin.

Use in pregnancy and lactation:

• The placental barrier can be crossed by most B complex vitamins.
• Each vitamin is safe during pregnancy.

Vitamin B complex use during breastfeeding:

• See individual agents for details.

Dose in kidney disease:

• See the dosage of individual vitamins.
• Most B complex vitamins can be safely used in patients with kidney disease.

Dose in liver disease:

• See the dosage of individual vitamins.
• Most B complex vitamins can be safely used in patients with liver disease.

Side effects of B complex vitamins:

See the side effects of individual vitamin.

Contraindication to B complex vitamins:

Allergies to any component of the formulation

Warnings and precautions

• Iron toxicity

  • Iron-containing B complex products can be dangerous if taken for a long time.
  • Iron toxicity can occur, particularly in children.
  • It should be kept out of reach of children in child-resistant containers
  • Children should not consume adult preparations.

• Pernicious anemia:

  • Patients with vitamin B12 deficiencies may experience irreversible neuronal damage if they consume B complex products that contain folic acids at higher than 0.1 mg/day.
  • Patients with folic acid should start vitamin B12 treatment immediately.

Monitor

Monitoring is usually not required.

How to administer B complex vitamins?

• It should be administered with meals to avoid gastrointestinal upset.

Mechanism of action of B complex vitamins:

Vitamin B complex is Vitamin B1 (thiamine), Vitamin B2(Riboflavin), Vitamin B3 [Niacin], Vitamin B3 [Vitamin B3], Vitamin B3 (“Riboflavin”), Vitamin B6 (“Pyridoxine”), Vitamin B9 (Folic acid”), Vitamin H (Biotin) and Vitamin B12 ("Cyanocobalamine”). Each section will discuss the details of the pharmacological characteristics.

B complex Brand Names (International):

• Antineurina
• B Complex
• B Complex 50
• B Complex P
• B-Complex
• Becozym
• Becozym Forte
• Becozyme
• Betex
• Betrimine
• Bevidoxine Forte
• Bex-C
• Everyday Stress Relief B Complex
• Farcovit B 12
• Health Plus Vitamins B Complex
• Mega B
• Mega B Complex
• Mintribee
• Multi B Complex
• Multi-Tabs B Complex
• Nervobion
• Nervobion Fuerte
• Nessiol
• Neubion
• Neurobion
• Neurobionta
• Neurorubine
• Neurorubine Forte
• Neurorubine-Forte Lactab
• Neurotrat
• Neurovit
• Neurovit Forte
• Rubrinal
• Rubrinex
• Super B Complex
• Trilagavit
• Vigranon B
• Vitadad B Forte
• Vitamin B Complex

B Complex Brands in Pakistan:

Details of the brands will be posted later. However, some of the commonly available brands include Neurobion, multibionta, vitrum, polybion, centrum, ledderlex, surbex T and surbex z, and theragran.